Research Review

Low Risk Of COVID-19 Spreading Through Tears

April 1, 2020

By Dwight Akerman, OD, MBA, FAAO
Chief Medical Editor, Review of Myopia Management

While researchers are certain that coronavirus spreads through mucus and droplets expelled by coughing or sneezing, it is unclear if the virus is spread through other bodily fluids, such as tears. A just-published study in Ophthalmology offers evidence that it is unlikely that infected patients are shedding virus through their tears, with one important caveat. None of the patients in the study had conjunctivitis, also known as pink eye. However, health officials believe pink eye develops in just 1 percent to 3 percent of people with coronavirus. The study’s authors conclude that their findings, coupled with the low incidence of pink eye among infected patients, suggests that the risk of virus transmission through tears is low.

To conduct the study, Ivan Seah, MBBS, Rupesh Agrawal, MD, and their colleagues at the National University Hospital and Tan Tock Seng Hospital in Singapore collected tear samples from 17 patients with COVID-19 from the time they showed symptoms until they recovered about 20 days later. Neither viral culture nor reverse transcription polymerase chain reaction (RT-PCR) detected the virus in their tears throughout the two-week course of the disease.

The infectious disease study team also took samples from the back of the nose and throat during the same time period. While the patients’ tears were clear of the virus, their noses and throats were teeming with COVID-19. Dr. Seah said he hopes their work helps to guide more research into preventing virus transmission through more significant routes, such as droplets and fecal-oral spread.

Despite this reassuring news, people need to understand that guarding your eyes — as well as your hands and mouth — can slow the spread of respiratory viruses like the coronavirus. When a sick person coughs or talks, virus particles can spray from their mouth or nose into another person’s face. You’re most likely to inhale these droplets through your mouth or nose, but they can also enter through your eyes. You can also become infected by touching something that has the virus on it — like a table or doorknob — and then touching your eyes.

ABSTRACT

Assessing Viral Shedding and Infectivity of Tears in Coronavirus Disease 2019 (COVID-19) Patients

Ivan Seah Yu Jun, MBBS, Danielle E. Anderson, PhD, Adrian Eng Zheng Kang, BSc, Lin-Fa Wang, PhD, Pooja Rao, MBBS, Barnaby Edward Young, MB, BChir, David Chien Lye, MBBS, Rupesh Agrawal, MD

Ocular transmission of COVID-19 is uncertain. Sixty-four tear samples were collected from 17 COVID-19 patients between Day 3 to Day 20 from initial symptoms. Neither viral culture nor reverse transcription polymerase chain reaction (RT-PCR) detected the virus, suggesting a low risk of ocular transmission.

Yu Jun IS, Anderson DE, Zheng Kang AE, Wang L-F, Rao P, Young BE, Lye DC, Agrawal R. (2020). Assessing Viral Shedding and Infectivity of Tears in Coronavirus Disease 2019 (COVID-19) Patients. Ophthalmology.

DOI: https://doi.org/10.1016/j.ophtha.2020.03.026

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