June 23, 2022
PALO ALTO, Calif. — In analyzing two-year data from SightGlass Vision’s CYPRESS clinical trial, experts have learned that the spectacle lenses were effective at controlling myopia in 6- and 7-year-olds. SightGlass Vision’s Diffusion Optics Technology (DOT) reduced both axial length (mean absolute reduction = 0.27 mm) and cycloplegic SER progression (mean absolute reduction = 0.77D) in 6- and 7-year-old children versus the control.
The focus on age is of particular interest to eye care professionals and researchers, as myopia progresses fastest in the youngest children.1,2 Since progression cannot be reversed, immediate intervention to slow or even stop progression is critical to a child’s short-term vision and long-term ocular health.
“Young myopes can be difficult to manage for many reasons. Parents and eye care professionals have traditionally had a limited number of myopia control solutions for younger children,” said Andrew Sedgwick, CEO of SightGlass Vision. “Our latest analysis suggests that spectacles enabled with SightGlass Vision Diffusion Optics Technology offer a promising new approach to myopia control for 6- and 7-year-olds.”
Study investigators enrolled, randomized, and dispensed the lenses to 256 eligible children across 14 clinical trial sites in the United States and Canada — a geographical distinction compared to most other myopia-related spectacle lens studies. At the time of enrollment, subjects were 6 to 10 years old having myopia between -0.75D and -4.50D, with nearly a third of them being 6 or 7 years old. With a mean age of 8.1 years at screening, the entire CYPRESS cohort is younger than children in many other well-known myopia management studies across various interventions. The trial is now in its third year.
Spectacle lenses using patent-protected SightGlass Vision Diffusion Optics Technology incorporate thousands of micro-dots that softly scatter light to reduce contrast on the retina — a method intended to reduce myopia progression in children.
Two Year Effectiveness of a Novel Myopia Management Spectacle Lens in Young Myopes (Rappon J, Neitz J, Neitz M, Chalberg T) will be presented for the first time at the 2022 Dutch Contact Lens Congress (NCC), which begins next week in Eindhoven, The Netherlands.
References
1 Hyman L, et al. Relationship of Age, Sex, and Ethnicity with Myopia Progression and Axial Elongation in the Correction of Myopia Evaluation Trial. Archives of Ophthalmology. 2005;123(7):977 987.
2 Verkicharla PK, Kammari P, Das AV. Myopia progression varies with age and severity of myopia. PLOS ONE. 2020;15(11):e0241759.
