Photo Credit: Dreamstime Photos
The Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting is being held in Salt Lake City, Utah, from May 4-8, 2025. Myopia management is one of the most popular research topics at the event, with many leaders in the industry sharing their myopia-related findings. While the meeting featured hundreds of presentations and posters on myopia management, Review of Myopia Management will be highlighting several noteworthy research findings throughout the event.
Here are some of the research highlights from day two of ARVO.
Axial Length
A comparison of axial length in children with 4 optical biometers.
Yasaman Adel, Sage Smith, David A. Berntsen, Eric R. Ritchey, Diane N. Sayah
This study aimed to evaluate the agreement between axial length (AL) measurements obtained from four optical biometers in school-aged children. A total of 27 children aged 6-18 years were recruited, with 25 completing the measurements after pupillary dilation. The biometers tested were ANTERION (Heidelberg Engineering), Lenstar LS900 (Haag-Streit), Aladdin (Topcon Healthcare) and Myopia Master (Oculus), with AL measured three times for each device in a randomized order. The results showed mean AL measurements of 23.63 ± 1.41mm for ANTERION, 23.61 ± 1.40mm for Lenstar, 23.61 ± 1.39mm for Aladdin and 23.61 ± 1.39mm for Myopia Master (p=0.045). Notably, a significant mean difference was found between ANTERION and Lenstar (p=0.017). While AL measurements from the four biometers were statistically different, these differences may not be clinically significant. Caution is advised when interpreting AL measurements from different optical biometers, as they may not be interchangeable in clinical practice.
Contact Lenses
Real-World Efficacy of Dual-Focus Daily Disposable Soft Contact Lenses in Controlling Myopia Progression
Aparna Raghuram, Debora Ghosh, Carissa Wu, Lauren Butler, Kimberley Chan
This study evaluated the effectiveness of dual focus soft contact lenses (MiSight 1 day) in controlling myopia progression in a clinical setting through a retrospective chart review of patients fitted with these lenses between 2019 and 2024. The inclusion criteria required patients to have both cycloplegic refraction and axial length (AL) measurements at baseline and after one year. A total of 25 patients (mean age: 9.64 years) met the criteria, with a baseline spherical equivalent refractive error (SER) of -3.11D. Over the one-year period, the mean change in SER was -0.32D, and the mean increase in AL was 0.16 mm. Notably, the study found that a 0.1 mm increase in AL corresponded to a SER change of -0.28D, indicating a significant relationship between eye growth and refractive error changes. Myopia progression was observed in various degrees among the participants, with 52% showing minimal progression (0 to -0.25D). These findings support the efficacy of MiSight 1 day contact lenses in slowing myopia progression, even in children with higher baseline myopia.
Spectacles
Reduction of Myopia of Prematurity Progression Using Highly Aspheric Lenses Target Technology (H.A.L.T)
Raffaele Parrozzani, Alessandro Carli, Carolina Molin, Eleonora Cosmo, Evelyn Longhin, Giulia Midena, Edoardo Midena
This study investigated the progression of myopia of prematurity (MOP) in children born prematurely and previously affected by retinopathy of prematurity (ROP). The research aimed to compare the effectiveness of Highly Aspheric Lenses Target (H.A.L.T) against conventional single vision lenses in managing MOP. Conducted at Padua University Hospital, the study included 58 children who met specific inclusion criteria, with a mean age of 6.2 years. Participants were divided into two groups: those using H.A.L.T lenses for at least 12 months and those using conventional single vision lenses. A regression model was employed to analyze the temporal evolution of refractive error in both groups. Results showed that myopia progressed by an average of -0.31D in the H.A.L.T group, compared to -0.92D in the single vision group, indicating a statistically significant difference (p=0.02). Both groups were similar in gestational age, birth weight and baseline refractive error. These findings suggest that H.A.L.T lenses may be more effective in slowing the progression of MOP in this population. Eye care professionals should consider the potential benefits of H.A.L.T technology for managing myopia in children with a history of ROP.
