Few studies have analyzed the effectiveness of outdoor light exposure intervention programs in slowing myopia progression.
A generally accepted definition of high myopia is needed.
Results of a single masked, randomized two-year controlled clinical trial
The real value of this study, however, lies in the follow-up findings after cessation of the outdoor intervention.
Presently, only atropine, pirenzepine, and 7-methylxanthine are shown to reduce myopia progression in human trials.
The researchers concluded that topical low-dose atropine appears to be safe and effective in a cohort of European schoolchildren.
The authors suggest the need for more rigorous clinical trials.
Combined interventions for myopia will potentially influence the standard of care.